The Clinical Features are briefly summarized here:
1. Patients usually present with signs of bone marrow failure with anemia, Thrombocytopenia and Neutropenia.
2. Fever is also one of the most common presenting symptom in acute Leukemia.
3. Some patients complain of bone pains, arthritis and limping which is most common with B-precursor acute lymphoblastic leukemia.
4. In patients with mature B-ALL there may be signs of CNS involvement like headache, vomiting, lethargy, nuchal rigidity etc.
5. Patients with a T cell lineage ALL there may be symptoms of respiratory distress due to a mediastinal mass.
6. Easy bruising or bleeding with petechiae due to decreased platelet counts.
7. Pallor, Lethargy and tiredness due to anemia.
8. Repeated infections along with fever because of low white cell count.
9. Loss of appetite and weight loss.
10. Swollen glands (lymphadenopathy) in the under arms, neck and groin.
Any child presenting with any on these symptoms needs to be evaluated properly with a detailed history, physical examination and appropriated diagnostic workup to diagnose the disease and start immediate treatment.
1. Patients usually present with signs of bone marrow failure with anemia, Thrombocytopenia and Neutropenia.
2. Fever is also one of the most common presenting symptom in acute Leukemia.
3. Some patients complain of bone pains, arthritis and limping which is most common with B-precursor acute lymphoblastic leukemia.
4. In patients with mature B-ALL there may be signs of CNS involvement like headache, vomiting, lethargy, nuchal rigidity etc.
5. Patients with a T cell lineage ALL there may be symptoms of respiratory distress due to a mediastinal mass.
6. Easy bruising or bleeding with petechiae due to decreased platelet counts.
7. Pallor, Lethargy and tiredness due to anemia.
8. Repeated infections along with fever because of low white cell count.
9. Loss of appetite and weight loss.
10. Swollen glands (lymphadenopathy) in the under arms, neck and groin.
Any child presenting with any on these symptoms needs to be evaluated properly with a detailed history, physical examination and appropriated diagnostic workup to diagnose the disease and start immediate treatment.
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